منابع مشابه
HLA and Infectious Diseases
The Human Leukocyte Antigen (HLA) system is the Major Histocompatibility Complex (MHC) in humans, and all knowledge on this system is of great interest to the field of medical sciences. HLA has become an important tool for understanding the pathogenesis of various infectious diseases; the alleles or HLA haplotypes inherited by an individual can predict several risk and protective factors relate...
متن کاملImmunomodulatory Properties of HLA-G in Infectious Diseases
HLA-G is a nonclassical major histocompatibility complex molecule first described at the maternal-fetal interface, on extravillous cytotrophoblasts. Its expression is restricted to some tissues in normal conditions but increases strongly in pathological conditions. The expression of this molecule has been studied in detail in cancers and is now also beginning to be described in infectious disea...
متن کاملCorticosteroids in Infectious Diseases
Accumulated data based on experiences with curtico,teroids in the management uf infectious diseases, have proved that they are very dfective and ,afe drugs provided that are administered properly. The Corticosteroids arc administered mainly bec,1usc o; antitoxic, antiimflammatory a11d antiallcrgic effects, the cndotoxius are ncuturalized, generalized body reactions are diminished, damaged t...
متن کاملEnhanced interaction of HLA-DM with HLA-DR in enlarged vacuoles of hereditary and infectious lysosomal diseases.
Following biosynthesis, class II MHC molecules are transported through a lysosome-like compartment, where they acquire antigenic peptides for presentation to T cells at the cell surface. This compartment is characterized by the presence of HLA-DM, which catalyzes the peptide loading process. Here we report that the morphology and function of the class II loading compartment is affected in disea...
متن کاملWomen and Infectious Diseases
mental, and demographic changes during the 20th century have affected the health of women. Many of the changes have benefited women's health, but some have had deleterious effects. Infectious diseases pose an especially formidable threat to women, claiming >15 million lives around the globe each year (1). For many infectious diseases, women are at higher risk and have a more severe course of il...
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ژورنال
عنوان ژورنال: Clinical Microbiology Reviews
سال: 2009
ISSN: 0893-8512,1098-6618
DOI: 10.1128/cmr.00048-08